Jason R. Cannon
- Professor of Health Sciences
Office and Contact
Education
PhD University of Michigan, Ann Arbor Toxicology 2006
PhD University of Michigan, Ann Arbor Toxicology 2006
Research Interests
Mechanisms of environmentally induced neurodegeneration; toxicology of neurological diseases
Mechanisms of environmentally induced neurodegeneration; toxicology of neurological diseases
Teaching Interests
General Toxicology, Analytical Toxicology, Biochemical Toxicology, Neurotoxicology, Toxicologic Pathology
General Toxicology, Analytical Toxicology, Biochemical Toxicology, Neurotoxicology, Toxicologic Pathology
Selected Grants
2025 - National Institute of Environmental Health Sciences - National Institutes of Health (MPI)
2024 - National Institute of Environmental Health Sciences - National Institutes of Health (PI)
2023 - National Institute of Environmental Health Sciences - National Institutes of Health (PI)
2022 - Department of Defense (PI)
2022 - National Institute on Aging - National Institutes of Health (co-I)
2022 - Department of Defense (co-I)
2021 - National Institute on Aging - National Institutes of Health (PI)
2021 - Branfman Foundation (co-I)
2021 - National Institute on Aging - National Institutes of Health (PI)
2024 - National Institute of Environmental Health Sciences - National Institutes of Health (PI)
2023 - National Institute of Environmental Health Sciences - National Institutes of Health (PI)
2022 - Department of Defense (PI)
2022 - National Institute on Aging - National Institutes of Health (co-I)
2022 - Department of Defense (co-I)
2021 - National Institute on Aging - National Institutes of Health (PI)
2021 - Branfman Foundation (co-I)
2021 - National Institute on Aging - National Institutes of Health (PI)
Selected Publications
Jakaria, M., and Cannon, J. R. (2026). Cytoprotective Mechanism of Necrox-5 Against Toxicity Induced by Experimental Ferroptosis Instigators and the Pesticide Propargite. International Journal of Molecular Sciences 27(4), 1772. Q2 Biochemistry & molecular biology.
Cappelli, S., Peradinovic, J., Mohovic, N., Mandal, P., Stuani, C., Longo, A., Cannon, J. R., Baloni, P., Leoni, B., Krsmanovic, T., Stojanov, K., Apic, G., Russell, R. B., Romano, M., Buratti, E., and Munitic, I. (2025). Optineurin Shapes Basal and LPS-Induced Transcriptomes in BV2 Microglia. International Journal of Molecular Sciences 26(21), 10453. Q2 Biochemistry & molecular biology.
Jakaria, M., and Cannon, J. R. (2025). Inhibition of Ferroptotic Toxicity by 4-Hydroxyindole. Chemical research in toxicology doi: 10.1021/acs.chemrestox.5c00313. Q2 Toxicology
Jakaria M, Cannon JR. Insights into Cytotoxicity and Redox Modulation by the Herbicide Linuron and Its Metabolite, 3,4-Dichloroaniline. Neurotoxicology. 2025:103324. doi: https://doi.org/10.1016/j.neuro.2025.103324. Q1 Toxicology.
Safreena, N., Chandra, G., Thirumalaikumar, V. P., and Cannon, J. (2025). Importance of post-translational protein modifications in PFAS toxicity. Toxicology doi: https://doi.org/10.1016/j.tox.2025.154260, 154260. Q1 Toxicology.
Jakaria, M., and Cannon, J. R. (2025). Neuromelanin-induced cellular stress and neurotoxicity in the pathogenesis of Parkinson's disease. Apoptosis doi: 10.1007/s10495-025-02156-3. Q1 Biochemistry & molecular biology.
Jakaria, M., and Cannon, J. R. (2025). The role of hydroxyindoles in protecting neuronal cultures from ferroptosis. Cell Death Discovery 11(1), 329. Q1 Cell Biology.
Currim, F., Brown-Leung, J., Syeda, T., Corson, M., Schumann, S., Qi, W., Baloni, P., Shannahan, J. H., Rochet, J.-C., Singh, R., and Cannon, J. R. (2025). Rotenone induced acute miRNA alterations in extracellular vesicles produce mitochondrial dysfunction and cell death. npj Parkinson's Disease 11(1), 59. Q1 Neurosciences.
Rivera, A. B., Stephens, A. B., Conrow, K. D., Griffith, S. T., Jameson, L. E., Cahill, T. M., Sammi, S. R., Swinburne, M. R., Cannon, J. R., and Leung, M. C. K. (2025). Regulatory Trends of Organophosphate and Pyrethroid Pesticides in Cannabis and Applications of the Comparative Toxicogenomics Database and Caenorhabditis elegans. Toxicological Sciences doi: 10.1093/toxsci/kfaf009. Q1 Toxicology.
Kanungo, J., Sorkin, B. C., Krzykwa, J., Mitchell, C. A., Embry, M., Spencer, P., Harry, G. J., Cannon, J., Liu, F., McPherson, C. A., Gafner, S., and Westerink, R. H. S. (2024). Screening tools to evaluate the neurotoxic potential of botanicals: building a strategy to assess safety. Expert Opin Drug Metab Toxicol 20(7), 629-646. Q3 Toxicology.